Cardiac Hypertrophy: Neonatal Pregnancy Disorder

Document Type : Original Article


Department of Biology, Faculty of Science, University of Jazan, KSA.


Cardiac hypertrophy is a chief dangerous factor for heart failure, which is the leading cause of child mortality among birth defects internationally.  It is a disorder that is defined by the heart muscle thickening, which expands the size of the heart chambers to improve the heart's capacity to pump blood into the body's tissues and organs. Pregnant women with a family history, of pre-gestational diabetes mellitus (PGDM), preeclampsia, or hypertension are at high risk of carrying a fetus with cardiac hypertrophy. These inborn developmental defects might include various cardiac defects along with fetal cardiomyopathy. Symptoms of the disease vary from minor to major and may include chest pain, as well as dyspnea. It is diagnosed based on medical history, a physical exam and echocardiogram results. Protection and treatment of the unborn fetus with cardiac hypertrophy can be achieved via lifestyle adjustment, obesity avoidance, medications and sometimes procedures. The aim of the current research is to address the etiology, diagnosis, pathogenesis and protection from cardiac hypertrophy as a teratological disorder in embryo.