Comparative Acute Exposure Study of Abamectin Different Formulations Inducing Physiological and Oxidative Stress Biomarkers in Nile Tilapia, (Oreochromis niloticus).

Ahmed, Farag A. Gh.; Reda, Rasha M.

doi:10.21608/eajbsz.2021.220560

Comparative Acute Exposure Study of Abamectin Different Formulations Inducing Physiological and Oxidative Stress Biomarkers in Nile Tilapia, (Oreochromis niloticus).

Document Type : Original Article

Authors

Farag A. Gh. Ahmed ¹
Rasha M. Reda ²

¹ Plant Protection Dept., Faculty of Agriculture, Zagazig University, P.O. Box, 44511, Zagazig, Egypt.

² Department of Fish Diseases and Management, Faculty of Veterinary Medicine, Zagazig University, P.O. Box 44511, Zagazig, Egypt.

10.21608/eajbsz.2021.220560

Abstract

The goal of this study is to assess the acute and sublethal potential hazards on tilapia fish (Oreochromis niloticus) exposed to two different commercial formulations of abamectin (ABM, 5%): emulsifiable concentration (EC) and microemulsions (ME). The median lethal concentration (LC₅₀ - 96 h) to each formulation was determined, as well as the adverse effects of sublethal concentrations (½ LC₅₀) on physiological and oxidative stress biomarkers after 96hs of exposure. The LC₅₀ (96 h) values for EC and ME were 10 and 16.6 µg/L, respectively. Furthermore, in both EC and ME, the findings of physiological and oxidative stress aspects revealed significant markedly increases in serum total protein, albumin, globulin, and urea, as well as a significant decline in aminotransferases activity (ALT and AST), and creatinine levels (Cre). Moreover, superoxide dismutase (SOD), malondialdehyde (MDA), catalase (CAT), and glutathione peroxidase (GPx) were greatly increased, whereas glutathione-S-transferase (GST) and glutathione (GSH) were significantly reduced in the liver and brain.

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