Some herbs reduce the hight of blood sugar, blood cholesterol in alloxan- diabetic rats.

Document Type : Original Article


Nutrition and food science, Home Economics Department, Jazan University


The present study was carried out to investigate the effect using 5% and 10% of different dried mixture from (dill and goadid) and (chicory and rosemary) on serum glucose and lipid profile, kidney function of diabetic rats.
A total of 36 male rats (120±5gm body weight) were used in this study. Rats were divided into two main groups, the first group (1) was used as control (-ve) group (6 rats) and fed on the basal diet only, the second group (2) (30 rats) was injected with 150mg/kg B.W. alloxan to induce hyperglycemic in rats and then divided into (5) subgroup, one of these group was used as control (+ve) group received on basal diet only, the other four subgroups fed on basal diet containing 5%or10% on one of the different mixture plant as previously. The experimental feeding period was 28 days. The results revealed that.
All treatment of experimental diets with different levels showed significant reduction in serum glucose, triglycerides, low-density lipoprotein (LDL-c) and very low-density lipoprotein (VLDL-c) as compared to the positive control group. These results are of great importance because cardiovascular diseases (CVD) are statistically related to the high TC. Level in blood serum.
Addition of experimental mixture (dill and goadid) (5% and10%) to the diets resulted in improvement of body weight gain.
All treatment of experimental diets especially addition 10% mixture of (dill and goadid) increased serum concentration of high-density lipoprotein cholesterol (HDL-c).
All treatment of experimental diets decreased the concentration of serum uric acid, urea nitrogen and creatinin concentrations in diabetic rats.